What Is Osteoarthritis?
Osteoarthritis is a degenerative joint disease characterized by the breakdown of joint cartilage and underlying bone. Unlike inflammatory arthritis, which is an autoimmune response, OA is primarily a mechanical and metabolic process where the body’s ability to repair joint tissues cannot keep up with the damage. This results in pain, swelling, and reduced flexibility.
Commonly Affected Areas Include:
- Knees: Leading to pain during walking or climbing stairs.
- Hips: Causing discomfort in the groin or buttocks and limiting range of motion.
- Hands: Affecting the base of the thumb and finger joints, often resulting in bony enlargements.
- Spine: Impacting the neck or lower back, sometimes leading to nerve compression.
At Bio Research Partner, we evaluate osteoarthritis as a multifactorial condition, addressing both mechanical stress and systemic contributors to develop personalized treatment plans.
Causes and Risk Factors
While aging is a primary factor, osteoarthritis is not an inevitable part of growing older. Several factors influence how quickly joint tissues degrade.
Risk Factors Include:
- Previous Joint Injuries: History of ACL tears, fractures, or sports injuries.
- Repetitive Stress: Occupational or athletic movements that put constant pressure on specific joints.
- Metabolic Health: Conditions like diabetes or high cholesterol can increase systemic inflammation.
- Obesity: Excess weight adds mechanical stress to weight-bearing joints and releases inflammatory proteins.
- Hormonal Changes: Estrogen deficiency during menopause is linked to increased joint degradation.
- Bone Deformities: Malformed joints or defective cartilage from birth.
Our approach integrates both orthopedic and systemic factors to optimize patient outcomes